Stixis suaveolens (Roxb.) Fruit Extract Deciphered Antidepressant and Antidiarrheal Effects via In vivo Approach

Depression is a pervasive psychiatric disorder worldwide and diarrhea considered leading cause of preventable death for infants children in developing countries. The current study was done to assess vivo activities crude methanol extract Stixis suaveolens fruit, focusing on antidepressant antidiarrheal effects. effect central nervous system (CNS) examined by recording the onset sleep total sleeping time. Besides, castor oil-induced mice model followed while evaluating Significant (p<0.01) reduction time (64.8 min) as well were recorded between test groups control. extract, when given orally, also resulted significant (p < 0.001) diarrheal feces induced oil 71.43%. bioassays demonstrated that fruit S. contains CNS stimulating actions. However, further vigorous studies are recommended isolate characterize major phytoconstituents from plant order develop exact mechanism actions against various disorders. Bangladesh Pharmaceutical Journal 26(1): 28-35, 2023 (January)